Lars Jordheim: search on Z-Library

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1

Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases

Jordheim, Lars Petter, Durantel, David, Zoulim, Fabien, Dumontet, Charles

Journal:

Nature Reviews Drug Discovery

Year:

2013

Language:

english

File:

PDF, 629 KB

english, 2013

2

Recent updates on purine and pyrimidine metabolism in physiological and pathological settings

Jordheim, Lars Petter, Peters, Godefridus J.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2020

Language:

english

File:

PDF, 910 KB

english, 2020

3

Simultaneous analysis of eight nucleoside triphosphates in cell lines by liquid chromatography coupled with tandem mass spectrometry

Sabine Cohen, Mehdi Megherbi, Lars Petter Jordheim, Isabelle Lefebvre, Christian Perigaud, Charles Dumontet, Jérôme Guitton

Journal:

Journal of Chromatography B

Year:

2009

Language:

english

File:

PDF, 613 KB

english, 2009

4

Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene

Carlos María Galmarini, Marilyn L Clarke, Lars Jordheim, Cheryl L Santos, Emeline Cros, John R Mackey, Charles Dumontet

Journal:

BMC Pharmacology

Year:

2004

Language:

english

File:

PDF, 1.08 MB

english, 2004

5

Unexpected Growth-Promoting Effect of Oxaliplatin in Excision Repair Cross-Complementation Group 1 Transfected Human Colon Cancer Cells

Jordheim, Lars Petter, Chettab, Kamel, Cros-Perrial, Emeline, Matera, Eva-Laure, Dumontet, Charles

Journal:

Year:

2018

Language:

english

File:

PDF, 449 KB

english, 2018

6

Polymeric nanocapsules as drug carriers for sustained anticancer activity of calcitriol in breast cancer cells

Nicolas, Sabrina, Bolzinger, Marie-Alexandrine, Jordheim, Lars Petter, Chevalier, Yves, Fessi, Hatem, Almouazen, Eyad

Journal:

International Journal of Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 634 KB

english, 2018

7

Synthesis and biological evaluation of new dipicolylamine zinc chelators as metallo-β-lactamase inhibitors

Prandina, Anthony, Radix, Sylvie, Le Borgne, Marc, Jordheim, Lars Petter, Bousfiha, Zineb, Fröhlich, Christopher, Leiros, Hanna-Kirsti S., Samuelsen, Ørjan, Frøvold, Espen, Rongved, Pål, Åstrand, Ove

Journal:

Year:

2019

Language:

english

File:

PDF, 1018 KB

english, 2019

8

Pyrimidine nucleoside analogs in cancer treatment

Galmarini, Carlos M, Jordheim, Lars, Dumontet, Charles

Journal:

Expert Review of Anticancer Therapy

Year:

2003

Language:

english

File:

PDF, 166 KB

english, 2003

9

Beta-hydroxyphosphonate ribonucleoside analogues derived from 4-substituted-1,2,3-triazoles as IMP/GMP mimics: synthesis and biological evaluation

Nguyen Van, Tai, Hospital, Audrey, Lionne, Corinne, Jordheim, Lars P, Dumontet, Charles, Périgaud, Christian, Chaloin, Laurent, Peyrottes, Suzanne

Journal:

Beilstein Journal of Organic Chemistry

Year:

2016

Language:

english

File:

PDF, 3.74 MB

english, 2016

10

Synthesis of substituted 5’‐aminoadenosine derivatives and evaluation of their inhibitory potential towards CD73

Ghoteimi, Rayane, Nguyen, Tai Van, Rahimova, Rahila, Grosjean, Felix, Cros-Perrial, Emeline, Uttaro, Jean-Pierre, Mathé, Christophe, Chaloin, Laurent, Jordheim, Lars Peter, Peyrottes, Suzanne

Journal:

Year:

2019

Language:

english

File:

PDF, 2.52 MB

english, 2019

11

Intracellular cytidine deaminase regulates gemcitabine metabolism in pancreatic cancer cell lines

Bjånes, Tormod K, Jordheim, Lars Petter, Schjøtt, Jan, Kamceva, Tina, Cros-Perrial, Emeline, Langer, Anika, de Garibay, Gorka Ruiz, Kotopoulis, Spiros, McCormack, Emmet, Riedel, Bettina

Journal:

Drug Metabolism and Disposition

Year:

2019

File:

PDF, 400 KB

2019

12

Further evidences for pharmacogenetic assessment of nucleoside analogue-treated patients

Lars Petter Jordheim

Journal:

Leukemia Research

Year:

2011

Language:

english

File:

PDF, 92 KB

english, 2011

13

In vitro susceptibility of CD4+ and CD8+ T cell subsets to fludarabine

Romina Gamberale, Carlos M. Galmarini, Paula Fernández-Calotti, Lars Jordheim, Julio Sánchez-Avalos, Charles Dumontet, Jorge Geffner, Mirta Giordano

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 196 KB

english, 2003

14

Bacterial Deoxyribonucleoside Kinases are Poor Suicide Genes in Mammalian Cells

Hébrard, Claire, Cros-Perrial, Emeline, Clausen, Anders Ranegaard, Dumontet, Charles, Piškur, Jure, Jordheim, Lars Petter

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2009

Language:

english

File:

PDF, 75 KB

english, 2009

15

Deoxycytidine kinase and cN-II nucleotidase expression in blast cells predict survival in acute myeloid leukaemia patients treated with cytarabine

Carlos María Galmarini, Xavier Thomas, Kathryn Graham, Assia El Jafaari, Emeline Cros, Lars Jordheim, John R. Mackey, Charles Dumontet

Journal:

British Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 237 KB

english, 2003

16

Review of recent studies on resistance to cytotoxic deoxynucleoside analogues

Lars Petter Jordheim, Charles Dumontet

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2007

Language:

english

File:

PDF, 895 KB

english, 2007

17

Structural Insights into the Inhibition of Cytosolic 5′-Nucleotidase II (cN-II) by Ribonucleoside 5′-Monophosphate Analogues

Gallier, Franck, Lallemand, Perrine, Meurillon, Maïa, Jordheim, Lars P., Dumontet, Charles, Périgaud, Christian, Lionne, Corinne, Peyrottes, Suzanne, Chaloin, Laurent, Briggs, James M.

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 1.44 MB

english, 2011

18

Regulation of tumor infiltrated innate immune cells by adenosine

Strakhova, Regina, Cadassou, Octavia, Cros-Perrial, Emeline, Jordheim, Lars Petter

Journal:

Purinergic Signalling

Year:

2020

File:

PDF, 514 KB

2020

19

4-Substituted-1,2,3-triazolo nucleotide analogues as CD73 inhibitors, their synthesis, in vitro screening, kinetic and in silico studies

Ghoteimi, Rayane, Braka, Abdennour, Rodriguez, CÃ©line, Cros-Perrial, Emeline, Tai Nguyen, Van, Uttaro, Jean-Pierre, MathÃ©, Christophe, Chaloin, Laurent, MÃ©nÃ©trier-Caux, Christine, Jordheim, Lars P

Journal:

Bioorganic Chemistry

Year:

2021

File:

PDF, 4.12 MB

2021

20

Role of intracellular cytidine deaminase activity for gemcitabine metabolism in pancreatic cancer cell lines

Bjånes, Tormod, Jordheim, Lars Petter, Schjøtt, Jan, Langer, Anika, Ruiz de Garibay, Gorka, Kotopoulis, Spiros, McCormack, Emmet, Riedel, Bettina

Journal:

Year:

2019

Language:

english

File:

PDF, 48 KB

english, 2019

21

The ribonucleotide reductase large subunit (RRM1) as a predictive factor in patients with cancer

Lars Petter Jordheim, Pascal Sève, Olivier Trédan, Charles Dumontet

Journal:

The Lancet Oncology

Year:

2011

Language:

english

File:

PDF, 238 KB

english, 2011

22

Preparation, Characterization and In Vitro Evaluation of a New Nucleotide Analogue Prodrug Cyclodextrin Inclusion Complexes

Diab, Roudayna, Jordheim, Lars P., Degobert, Ghania, Peyrottes, Suzanne, Périgaud, Christian, Dumontet, Charles, Fessi, Hatem

Journal:

Journal of Nanoscience and Nanotechnology

Year:

2009

Language:

english

File:

PDF, 1.42 MB

english, 2009

23

Inclusion complexes of a nucleotide analogue with hydroxypropyl-beta-cyclodextrin

Lars Petter Jordheim, Ghania Degobert, Roudayna Diab, Suzanne Peyrottes, Christian Périgaud, Charles Dumontet, Hatem Fessi

Journal:

Journal of Inclusion Phenomena and Macrocyclic Chemistry

Year:

2009

Language:

english

File:

PDF, 203 KB

english, 2009

24

Influence of p53 and p21WAF1 expression on sensitivity of cancer cells to cladribine

Carlos Marı́a Galmarini, Nathalie Voorzanger, Nicole Falette, Lars Jordheim, Emeline Cros, Alain Puisieux, Charles Dumontet

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 299 KB

english, 2003

25

Virtual Screening and Biological Evaluation of Inhibitors Targeting the XPA-ERCC1 Interaction

Barakat, Khaled H., Jordheim, Lars P., Perez-Pineiro, Rolando, Wishart, David, Dumontet, Charles, Tuszynski, Jack A., Nie, Daotai

Journal:

Year:

2012

Language:

english

File:

PDF, 988 KB

english, 2012

26

Gemcitabine is active against clinical multiresistant Staphylococcus aureus strains and is synergistic with gentamicin

Lars Petter Jordheim, Sabrina Ben Larbi, Olivier Fendrich, Claire Ducrot, Emmanuelle Bergeron, Charles Dumontet, Jean Freney, Anne Doléans-Jordheim

Journal:

International Journal of Antimicrobial Agents

Year:

2012

Language:

english

File:

PDF, 278 KB

english, 2012

27

Nano-encapsulation of Vitamin D3Active Metabolites for Application in Chemotherapy: Formulation Study andin VitroEvaluation

Almouazen, Eyad, Bourgeois, Sandrine, Jordheim, Lars Petter, Fessi, Hatem, BrianÃ§on, Stephanie

Journal:

Pharmaceutical Research

Year:

2013

Language:

english

File:

PDF, 400 KB

english, 2013

28

Expression of domains for protein-protein interaction of nucleotide excision repair proteins modifies cancer cell sensitivity to platinum derivatives and genomic stability

Jordheim, Lars Petter, Cros-Perrial, Emeline, Matera, Eva-Laure, Bouledrak, Karima, Dumontet, Charles

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2014

Language:

english

File:

PDF, 351 KB

english, 2014

29

Functions of the multi-interacting protein KIDINS220/ARMS in cancer and other pathologies

Raza, Muhammad-Zawwad, Allegrini, Simone, Dumontet, Charles, Jordheim, Lars Petter

Journal:

Genes, Chromosomes and Cancer

Year:

2017

Language:

english

File:

PDF, 982 KB

english, 2017

30

Special feature of mixed phosphotriester derivatives of cytarabine

Marie-Hélène Gouy, Lars P. Jordheim, Isabelle Lefebvre, Emeline Cros, Charles Dumontet, Suzanne Peyrottes, Christian Périgaud

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 390 KB

english, 2009

31

Problems Related to Resistance to Cytarabine in Acute Myeloid Leukemia

Cros, Emeline, Jordheim, Lars, Dumontet, Charles, Galmarini, Carlos M

Journal:

Leukemia and Lymphoma

Year:

2004

Language:

english

File:

PDF, 267 KB

english, 2004

32

Cytosolic 5′-Nucleotidase II Silencing in a Human Lung Carcinoma Cell Line Opposes Cancer Phenotype with a Concomitant Increase in p53 Phosphorylation

Pesi, Rossana, Petrotto, Edoardo, Colombaioni, Laura, Allegrini, Simone, Garcia-Gil, Mercedes, Camici, Marcella, Jordheim, Lars, Tozzi, Maria

Journal:

International Journal of Molecular Sciences

Year:

2018

Language:

english

File:

PDF, 2.67 MB

english, 2018

33

Expanding the clinical relevance of the 5′-nucleotidase cN-II/NT5C2

Jordheim, Lars Petter

Journal:

Purinergic Signalling

Year:

2018

Language:

english

File:

PDF, 543 KB

english, 2018

34

Gemcitabine resistance due to deoxycytidine kinase deficiency can be reverted by fruitfly deoxynucleoside kinase, DmdNK, in human uterine sarcoma cells

Lars Petter Jordheim, Carlos M. Galmarini, Charles Dumontet

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 277 KB

english, 2006

35

Sensitivity and gene expression profile of fresh human acute myeloid leukemia cells exposed ex vivo to AS602868

Lars Petter Jordheim, Adriana Plesa, Michel Dreano, Emeline Cros-Perrial, Céline Keime, Stéphanie Herveau, Delphine Demangel, Julie A. Vendrell, Charles Dumontet

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 613 KB

english, 2011

36

Substrate cycles and drug resistance to 1-beta-D-arabinofuranosylcytosine (araC)

Fernandez-Calotti, Paula, Jordheim, Lars Petter, Giordano, Mirta, Dumontet, Charles, Galmarini, Carlos Maria

Journal:

Leukemia and Lymphoma

Year:

2005

Language:

english

File:

PDF, 211 KB

english, 2005

37

Determination of the enzymatic activity of cytosolic 5′-nucleotidase cN-II in cancer cells: development of a simple analytical method and related cell line models

Jordheim, Lars Petter, Puy, Jean-Yves, Cros-Perrial, Emeline, Peyrottes, Suzanne, Lefebvre, Isabelle, Périgaud, Christian, Dumontet, Charles

Journal:

Analytical and Bioanalytical Chemistry

Year:

2015

Language:

english

File:

PDF, 670 KB

english, 2015

38

Stably transfected adherent cancer cell models with decreased expression of 5′-nucleotidase cN-II

Bricard, Gabriel, Cros-Perrial, Emeline, Machon, Christelle, Dumontet, Charles, Jordheim, Lars Petter

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2016

Language:

english

File:

PDF, 637 KB

english, 2016

39

CD73 inhibition by purine cytotoxic nucleoside analogue-based diphosphonates

Dumontet, Charles, Peyrottes, Suzanne, Rabeson, Céline, Cros-Perrial, Emeline, Géant, Pierre Yves, Chaloin, Laurent, Jordheim, Lars Petter

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.66 MB

english, 2018

40

Synthesis and biological evaluation of new dipicolylamine zinc chelators as metallo-β-lactamase inhibitors

Prandina, Anthony, Radix, Sylvie, Le Borgne, Marc, Jordheim, Lars Petter, Bousfiha, Zineb, Fröhlich, Christopher, Leiros, Hanna-Kirsti S., Samuelsen, Ørjan, Frøvold, Espen, Rongved, Pål, Åstrand, Ove

Journal:

Year:

2019

File:

PDF, 1018 KB

2019

41

F-ara-AMP is a substrate of cytoplasmic 5′-nucleotidase II (cN-II): HPLC and NMR studies of enzymatic dephosphorylation

Jordheim, Lars P., Cros, Emeline, Galmarini, Carlos M., Dumontet, Charles, Bretonnet, Anne-Sophie, Krimm, Isabelle, Lancelin, Jean-Marc, Gagnieu, Marie-Claude

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2006

Language:

english

File:

PDF, 262 KB

english, 2006

42

Detecting differential allelic expression using high-resolution melting curve analysis: application to the breast cancer susceptibility gene CHEK2

Tú Nguyen-Dumont, Lars P Jordheim, Jocelyne Michelon, Nathalie Forey, Sandrine McKay-Chopin, Kathleen Cuningham Foundation Consortium for Research into Familial Aspects of Breast Cancer (kConFab), Olg

Journal:

BMC Medical Genomics

Year:

2011

Language:

english

File:

PDF, 1.63 MB

english, 2011

43

The druggability of intracellular nucleotide-degrading enzymes

Rampazzo, Chiara, Tozzi, Maria Grazia, Dumontet, Charles, Jordheim, Lars Petter

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 513 KB

english, 2016

44

Liquid chromatographic methods for the determination of endogenous nucleotides and nucleotide analogs used in cancer therapy: A review

Sabine Cohen, Lars P. Jordheim, Mehdi Megherbi, Charles Dumontet, Jérôme Guitton

Journal:

Journal of Chromatography B

Year:

2010

Language:

english

File:

PDF, 344 KB

english, 2010

45

Characterization of an inhibitory dynamic pharmacophore for the ERCC1–XPA interaction using a combined molecular dynamics and virtual screening approach

Khaled H. Barakat, J. Torin Huzil, Tyler Luchko, Lars Jordheim, Charles Dumontet, Jack Tuszynski

Journal:

Journal of Molecular Graphics and Modelling

Year:

2009

Language:

english

File:

PDF, 1.15 MB

english, 2009

46

Structure–activity relationships of β-hydroxyphosphonate nucleoside analogues as cytosolic 5′-nucleotidase II potential inhibitors: Synthesis, in vitro evaluation and molecular modeling studies

Meurillon, Maïa, Marton, Zsuzsanna, Hospital, Audrey, Jordheim, Lars Petter, Béjaud, Jérôme, Lionne, Corinne, Dumontet, Charles, Périgaud, Christian, Chaloin, Laurent, Peyrottes, Suzanne

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.81 MB

english, 2014

47

Role of IMP-SELECTIVE 5′-NUCLEOTIDASE (cN-II) in HEMATOLOGICAL MALIGNANCIES

Galmarini, Carlos M., Jordheim, Lars, Dumontet, Charles

Journal:

Leukemia and Lymphoma

Year:

2003

Language:

english

File:

PDF, 175 KB

english, 2003

48

Determination and quantification of intracellular fludarabine triphosphate, cladribine triphosphate and clofarabine triphosphate by LC–MS/MS in human cancer cells

Puy, Jean-Yves, Jordheim, Lars Petter, Cros-Perrial, Emeline, Dumontet, Charles, Peyrottes, Suzanne, Lefebvre-Tournier, Isabelle

Journal:

Journal of Chromatography B

Year:

2017

Language:

english

File:

PDF, 1.50 MB

english, 2017

49

Identification of non-competitive inhibitors of cytosolic 5'-nucleotidase II using a fragment-based approach

Marton, Zsuzsanna, Guillon, Rémi, Krimm, Isabelle, Preeti, Preeti, Rahimova, Rahila, Egron, David, Jordheim, Lars Petter, Aghajari, Nushin, Dumontet, Charles, Périgaud, Christian, Lionne, Corinne, Pey

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.35 MB

english, 2015

50

Identification and characterization of inhibitors of cytoplasmic 5′-nucleotidase cN-II issued from virtual screening

Jordheim, Lars Petter, Marton, Zsuzsanna, Rhimi, Moez, Cros-Perrial, Emeline, Lionne, Corinne, Peyrottes, Suzanne, Dumontet, Charles, Aghajari, Nushin, Chaloin, Laurent

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.17 MB

english, 2013

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